Write a 6 pages paper on the scope and limitations of quantitative nuclear magnetic resonance technique. The measurements provided by the Nuclear Magnetic Resonance Technique can avail information on various active processes. The active processes can have rates ranging from 10-2 to 10-10 per second. Quantitatively, NMR has done away with the need for calibrations that are usually strenuous. How has it done this? NMR has been shown to have the exceptional capability of containing an even molar reaction for all similar nuclei. Due to this exceptional capability, a solitary standard can be utilized for the precise quantitation of substances (Merkley, et al., 2013).
The principle behind NMR is that it senses electrical currents that have been triggered by nuclear magnetic flashes that are found in an even magnetic field that is static (Kleckner & Foster, 2010). Thus, nuclei that have non-zero magnetic flashes are termed to be active to magnetic resonance. hence, they can be sensed. Each nucleus that is active in magnetic resonance has a special frequency. The special frequency is influenced by the magnetic field’s strength, it’s typical electronic setting, and its isotope’s magnetic features (Dongsheng, et al., 2010). The type of nucleus determines the typical frequency. Hence, NMR can easily differentiate between two Hydrogen isotopes (Merkley, et al., 2013).
Because the typical setting of the nuclei affects the precise frequency in the collection of similar nuclei, the applications, and importance of NMR has become widespread and diverse (Merkley, et al., 2013). Thus, the application of NMR in quantitative analysis is just one of the many applications there are. The report will focus on quantitative NMR and examine its scope and limit as it has been applied in various research studies.
The number of studies that make use of quantitative NMR is not that much. Hence, it can be said that the use of NMR for quantitative evaluation is not that common. Nevertheless, quantitative NMR can precisely and correctly evaluate the concentration of the analyte. The molecules could be in an intricate mixture or in a sample that has been purified. Quantitative NMR does away with the need for strenuous calibrations (Bohni, et al., 2013). Usually, the state of the samples for quantitative evaluation can be semi-solid state or in solid-state.