Advanced pharmacology case study.

for the appropriate diagnostic tests that could be applied towards the assessment of her condition and thus. provide her with appropriate education on how to handle her condition (Rice, 2010).

Sally Smith, is noted to be suffering from these conditions and a complete and informed diagnostic assessment and prescription for appropriate medication should be founded on the pathophysiology of the conditions. Pathophysiology refers to the study of the processes that result in a medical condition and the complications that may be associated with the same.

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An understanding of the pathophysiology of asthma entails the study of changes such as bronchoconstriction, inflammation, and discussions on the immune system, triggers of asthma, IgE, airway remodeling and allergies (Kee et al., 2014). Based on these, the largely known changes that take place when a person is attacked by asthma include:

Gastro-esophageal reflux disorder (GERD) refers to the symptomatic or histological change in the esophagus that is associated with the retrograde movement of gastric contents (Golan, 2011). This reflux is usually minimized through the contraction of the lower esophageal sphincter and esophageal peristaltic waves in the process of relaxation to allow food enter the stomach. Based on pathophysiology, GERD may develop in either condition as:

This condition is largely caused by the impairment of the central monoaminergic functions of the lesions. Considering multiple interactions with the brain, a condition with Sally may be perceived as caused by a complex phenomenon with more than one etiology. It comprises of predisposed episodic and progressive disturbances to the moods of the patient.

These include tremor of about 20%, nausea and dizziness, fever/headache, nervousness, bronchospasm, cough, allergic reactions, urinary tract infections, dry mouth, increased sweating and eructation or flatulence (Atkinson, 2012).

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